2-thiophene ethanol is a colorless or light yellow clear liquid. The method for synthesis of 2-thiophene ethanol which is an important medicine intermediate was introduced, such as butyl lithium process, Grignard process,natrium reagent process and reduction ester process. Among them, the first three methods all took thiophene as raw material, the metal compounds of thiophene could be obtained through different steps, then reacted with ethylene oxide, and finally hydrolyze into 2-thiophene ethanol. during reduction ester process, thiophene-acetate was used as raw material, with catalyst, the ester reduced into primary alcohol. 2-thiophene ethanol can be used for the synthesis of a variety of drugs. It is the preparation of [3,2-c] thiophene and pyridine compounds key intermediates.It is also a variety of new drugs with platelet and thrombosis related to heart disease and anti-inflammatory analgesic precursor materials. Two kinds of thienopyridine derivatives: Ticlopidine Hydrochloride and Clopidogrel. It as anti-platelet drugs used for the treatment and prevention of coronary heart disease. Ticlopidine Hydrochloride is a new aggregation inhibitors, clinically used in the treatment of cardiovascular and cerebrovascular diseases and thrombosis. In 1974, developed and been on sale by Sanofi Company, the trade name is Ticlid. Currently the drug is approved for marketing in more than 30 countries around the world. Ticlopidine can effectively inhibit platelet aggregation in patients with angina pectoris, platelet aggregation inhibition efficiency up to 94.4%, and can be used for the treatment of angina pectoris. Ticlopidine is the only one has been shown to be beneficial in the the ACS early and late treatment anticoagulant, and it is aspirin allergy alternative medication. It is next-generation thienopyridine derivatives developed by Sanofi company based on ticlopidine, its mechanism of drug action is similar toticlopidine and the efficacy is also considerable, but the role of strong and tolerability is higher than ticlopidine. For a long time, the pharmaceutical industry has been the focus of the development of fine chemicals industry. At present, the structure of new drug development is a huge investment, a longer period, the low success rate. Therefore, lead compounds for existing drugs known structure, its structural modification or transformation of a new drug is an important way for new drug research and development. With the development of downstream products, pharmaceutical intermediates industry will be further strengthened. 2-thiophene ethanol(CAS NO.5402-55-1) as an important drug intermediates in the synthesis of high value-added of platelet aggregation inhibitors and antithrombotic drugs thienopyridine process can bring great economic benefits.